20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36542 | Prostaglandin A2 | Medullin | |
PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some anti... | |||
T36041 | 16,16-dimethyl Prostaglandin A2 | 16,16-dimethyl Prostaglandin A2 | |
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4... | |||
T36158 | 8-iso Prostaglandin A2 | 8-iso Prostaglandin A2 | |
8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid. | |||
T6236 | Ozagrel | OKY-046,Domenan | Thrombin , Prostaglandin Receptor |
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch... | |||
T6625 | Ozagrel hydrochloride | Ozagrel HCl,OKY-046 HCl | Thrombin , Prostaglandin Receptor |
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. | |||
T11825 | LCB-2853 | PPAR | |
LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects. | |||
TQ0145 | (R)-(+)-Bay-K-8644 | (R)-(+)-Bay K 8644 | Calcium Channel , PPAR |
(R)-(+)-Bay-K-8644 is a Ca2+ channel agonist, a dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism o... | |||
T1002 | Etodolac | Ultradol,AY-24236,Etodolic acid,Lodine | Retinoid Receptor , COX |
Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ... | |||
T0839 | Ketoprofen | RP-19583 | Apoptosis , COX , MRP |
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas... | |||
T28841 | SQ 26655 | SQ26655,SQ-26655 | |
SQ 26655 is an antagonist of thromboxane A2/prostaglandin H2. | |||
T22896 | L-655,240 | Others | |
L-655,240 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist. | |||
T70871 | Mipitroban | ||
Mipitroban is a thromboxane A2/prostaglandin H2 antagonist. | |||
T22897 | L-670,596 | Others | |
L-670,596 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist. | |||
T70709 | FCE-27262 | ||
FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist. | |||
T70694 | HA-29 | ||
HA-29 is an inhibitor of thromboxane A2 and prostaglandin endoperoxide receptors. | |||
T28242 | Ono 3708 | Ono-3708,Ono3708 | |
Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo. | |||
T15829 | L 888607 Racemate | Aurora Kinase | |
L 888607 Racemate is a selective antagonist of prostaglandin D2 receptor subtype 1 (DP1) (Kis: 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively). | |||
T34862 | Thromboxane A2 | Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2 | |
Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction. | |||
T13488 | 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide | 2-_E-2-decenoylamino_ethyl_2-_cyclohexylethyl__sulfide | Prostaglandin Receptor |
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound known to inhibit stress-induced ulcers, effectively maintaining the levels of phospholipase A2 and prostaglandin E2 in rats subjected to water immersio... | |||
T28240 | Ono 1301 | Ono-1301,Ono1301 | |
Ono 1301 is a prostaglandin I2 mimetic coumpound with inhibitory activity against thromboxane A2 synthase. Ono 1301 suppresses pancreatic fibrosis in the DBTC-induced CP model by inhibiting monocyte activity not only wit... |